PAK2
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
| Full Name | p21 (RAC1) activated kinase 2 |
| Gene ID | Human: 5062 Mouse: 224105 Rat: 29432 Monkey: 710314 |
| UniProt ID | Human: Q13177 Mouse: Q8CIN4 Rat: Q64303 |
| Alternative Names | KNO2; PAK65; PAKgamma;serine/threonine-protein kinase PAK 2;PAK-2;S6/H4 kinase;gamma-PAK;p21 (CDKN1A)-activated kinase 2;p21 protein (Cdc42/Rac)-activated kinase 2;p21-activated kinase 2;p58 |
Product List
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Magic™ Human PAK2 Assay
[CAT#: S01YF-1222-KX416]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PAK2 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human PAK2 Stable Cell Line
[CAT#: S01YF-1023-PY41]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;AsPC-1 Assay Types: Biological assays
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