OXGR1
This gene encodes a G protein-coupled receptor that is a member of the GPCR superfamily's oxoglutarate receptor family. The citric acid intermediate oxoglutarate and a number of cysteinyl leukotrienes, such as leukotrienes E4, C4, and D4, which are linked to various inflammatory diseases, activate the encoded protein. A knockout of this gene results in hearing loss, alterations to the mucosal epithelium, middle ear inflammation, and an increase in fluid behind the eardrum in mice.
| Full Name | Oxoglutarate receptor 1 |
| Gene ID | Human: 27199 Mouse: 239283 Rat: 290493 Monkey: 104681004 |
| UniProt ID | Human: Q96P68 Mouse: Q6IYF8 Rat: Q6Y1R5 Monkey: A0A2K6NMY2 |
| Alternative Names | OXGR1; aKGR; GPR80; GPR99; P2Y15; P2RY15; 2-oxoglutarate receptor 1; G protein-coupled receptor 80; G-protein coupled receptor 99; P2Y purinoceptor 15; P2Y-like GPCR; P2Y-like nucleotide receptor; alpha-ketoglutarate receptor 1; oxoglutarate (alpha-ketoglutarate) receptor 1; seven transmembrane helix receptor; Oxoglutarate receptor 1 |
Product List
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Magic™ Human OXGR1 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX235]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OXGR1 Target Family: Class A Orphan Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
mProX™ Human OXGR1 Stable Cell Line
[CAT#: S01YF-0923-KX61]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OXGR1 Target Family: α-Ketoglutarate Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
Magic™ Human FLAG tagged OXGR1 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX293]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: OXGR1 Target Family: Citric Acid Cycle Intermediates Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
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