ORAI1
The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).
| Full Name | ORAI calcium release-activated calcium modulator 1 |
| Gene ID | Human: 84876 Mouse: 109305 Rat: 304496 Monkey: 700190 |
| UniProt ID | Human: Q96D31 Mouse: Q8BWG9 Rat: Q5M848 Monkey: A0A1D5QNU6 |
| Alternative Names | ORAI1; IMD9; TAM2; ORAT1; CRACM1; TMEM142A; calcium release-activated calcium channel protein 1; calcium release-activated calcium modulator 1; protein orai-1; transmembrane protein 142A; ORAI calcium release-activated calcium modulator 1 |
Product List
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Magic™ Human STIM1/ORAI1 HEK293 Cell Line with Photoprotein Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX324]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: STIM1/ORAI1 Target Family: Ion Channel Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Calcium flux assay
mProX™ Human ORAI1 Stable Cell Line
[CAT#: S01YF-1023-PY259]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HT22 Assay Types: Biological assays
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