NTRK2
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Full Name | neurotrophic receptor tyrosine kinase 2 |
Gene ID | Human: 4915 Mouse: 18212 Rat: 25054 Monkey: 709757 |
UniProt ID | Human: Q16620 Mouse: P15209 Rat: Q63604 |
Alternative Names | OBHD; TRKB; DEE58; trk-B; EIEE58; GP145-TrkB;BDNF/NT-3 growth factors receptor;BDNF-tropomyosine receptor kinase B;neurotrophic tyrosine kinase receptor type 2;tropomyosin-related kinase B;tyrosine kinase receptor B |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NACC2 & NTRK2 Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: QKI & NTRK2 (G639R) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: QKI & NTRK2 (G709C) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: QKI & NTRK2 Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Ba/F3