NR3C2
The mineralocorticoid receptor, which is encoded by this gene, mediates the effects of aldosterone on water and salt balance in constrained target cells. The protein activates target genes by binding to mineralocorticoid response sites in a ligand-dependent transcription factor. Autosomal dominant pseudohypoaldosteronism type I, a condition characterized by urinary salt wasting, is brought on by mutations in this gene. Additionally, early onset hypertension with significant pregnancy-related aggravation is linked to this gene's defects.
| Full Name | Nuclear receptor subfamily 3 group C member 2 |
| Gene ID | Human: 4306 Mouse: 110784 Rat: 25672 Monkey: 704789 |
| UniProt ID | Human: P08235 Mouse: Q8VII8 Rat: P22199 Monkey: A0A5F8ATS5 |
| Alternative Names | MR; MCR; MLR; NR3C2VIT; mineralocorticoid receptor; aldosterone receptor; mineralocorticoid receptor 1; mineralocorticoid receptor 2; mineralocorticoid receptor delta |
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mProX™ Human NR3C2 Stable Cell Line
[CAT#: S01YF-1123-KX93]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NR3C2 Target Family: 3-Ketosteroid Receptor Target Protein Species: Human Host Cell Type: Panc-1; MiaPaCa-2; CHO-K1; HEK293
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