mProX™ Human NR3C2 Stable Cell Line

[CAT#: S01YF-1123-KX93]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Nuclear Receptor

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Lot Number

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Product Information

Target Protein

NR3C2

Target Family

3-Ketosteroid Receptor

Target Protein Species

Human

Host Cell Type

Panc-1; MiaPaCa-2; CHO-K1; HEK293

Target Classification

Nuclear Receptor

Target Research Area

Inflammation Research; Reproductive Research

Related Diseases

Pseudohypoaldosteronism

Gene ID

4306

UniProt ID

P08235

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Instructions for producing the protein known as the mineralocorticoid receptor are found in the NR3C2 gene. Specialized proteins in the cell membrane that govern the entry of potassium or sodium into cells are regulated by the mineralocorticoid receptor. The mineralocorticoid receptor, particularly in some kidney cells, increases the quantity and activity of these proteins at the cell membrane in response to signals that the body's sodium levels are low. While one of these proteins moves sodium into the cell, the other protein moves potassium into the cell and sodium out of the cell at the same time. These proteins aid in the removal of potassium from the body through secretion and the maintenance of sodium in the body through reabsorption. The customized NR3C2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Cynthia

This is a very reliable NR3C2 cell line with high sensitivity and specificity, suitable for experiments such as immunofluorescence microscopy and flow cytometry. Feb 12 2020

chat Verified Customer

chat Robert

Recommended for all labs based on my experience of using this NR3C2 cell line. Jan 05 2021

chat Verified Customer

FAQ

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