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NR3C1

This gene encodes the glucocorticoid receptor, a transcription factor that activates the transcription of glucocorticoid responsive genes by binding to glucocorticoid response elements in their promoters, as well as a transcription factor regulator. Normally present in the cytoplasm, this receptor is moved into the nucleus when it binds to a ligand. In target tissues, it affects inflammatory reactions, cellular proliferation, and differentiation. Glucocorticoid resistance in general is linked to mutations in this gene.

Full Name Nuclear receptor subfamily 3 group C member 1
Gene ID Human: 2908
Mouse: 14815
Rat: 24413
Monkey: 706198
UniProt ID Human: P04150
Mouse: P06537
Rat: P06536
Monkey: H9FTF1
Alternative Names GR; GCR; GRL; GCCR; GCRST; glucocorticoid receptor; nuclear receptor subfamily 3 group C member 1 variant hGR-B(54); nuclear receptor subfamily 3 group C member 1 variant hGR-B(77); nuclear receptor subfamily 3 group C member 1 variant hGR-B(93); nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: NR3C1 Target Family: 3-Ketosteroid Receptor Target Protein Species: Human Host Cell Type: CCRF-CEM; 6T-CEM; NALM6; CHO-K1; HEK293
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