NR3C1
This gene encodes the glucocorticoid receptor, a transcription factor that activates the transcription of glucocorticoid responsive genes by binding to glucocorticoid response elements in their promoters, as well as a transcription factor regulator. Normally present in the cytoplasm, this receptor is moved into the nucleus when it binds to a ligand. In target tissues, it affects inflammatory reactions, cellular proliferation, and differentiation. Glucocorticoid resistance in general is linked to mutations in this gene.
Full Name | Nuclear receptor subfamily 3 group C member 1 |
Gene ID | Human: 2908 Mouse: 14815 Rat: 24413 Monkey: 706198 |
UniProt ID | Human: P04150 Mouse: P06537 Rat: P06536 Monkey: H9FTF1 |
Alternative Names | GR; GCR; GRL; GCCR; GCRST; glucocorticoid receptor; nuclear receptor subfamily 3 group C member 1 variant hGR-B(54); nuclear receptor subfamily 3 group C member 1 variant hGR-B(77); nuclear receptor subfamily 3 group C member 1 variant hGR-B(93); nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NR3C1 Target Family: 3-Ketosteroid Receptor Target Protein Species: Human Host Cell Type: CCRF-CEM; 6T-CEM; NALM6; CHO-K1; HEK293