NR1H3
This gene encodes a protein that is a member of the nuclear receptor superfamily's NR1 subfamily. Members of the NR1 family act as important macrophage regulators by regulating transcriptional activities related to inflammation and lipid balance. The liver, kidney, and intestine are just a few of the visceral organs where this protein is strongly expressed. It modulates the expression of target genes containing retinoid response elements by forming a heterodimer with the retinoid X receptor (RXR). Studies on mice lacking this gene indicate that it might be crucial for controlling cholesterol homeostasis.
| Full Name | Nuclear receptor subfamily 1 group H member 3 |
| Gene ID | Human: 10062 Mouse: 22259 Rat: 58852 Monkey: 713679 |
| UniProt ID | Human: Q13133 Mouse: Q9Z0Y9 Rat: Q62685 Monkey: F6ST28 |
| Alternative Names | LXRA; LXR-a; RLD-1; oxysterols receptor LXR-alpha |
Product List
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mProX™ Human NR1H3 Stable Cell Line
[CAT#: S01YF-1123-KX101]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NR1H3 Target Family: Liver X Receptor Target Protein Species: Human Host Cell Type: Ishikawa; CHO-K1; HEK293
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