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NR1H2

The liver X receptors are a nuclear receptor superfamily subfamily that play a critical role in regulating lipid homeostasis and inflammation as well as macrophage activity. In contrast to LXRB, which is found everywhere, inducible LXRA is highly expressed in the liver, adrenal gland, gut, adipose tissue, macrophages, lung, and kidney. Target genes containing LXR response elements are regulated by the production of ligand-activated LXRs, which join forces with retinoid X receptors to form obligatory heterodimers.

Full Name Nuclear receptor subfamily 1 group H member 2
Gene ID Human: 7376
Mouse: 22260
Rat: 58851
Monkey: 719210
UniProt ID Human: P55055
Mouse: Q60644
Rat: Q62755
Monkey: F7F982
Alternative Names NER; UNR; LXRB; LXR-b; NER-I; RIP15; oxysterols receptor LXR-beta; LX receptor beta; liver X nuclear receptor beta; nuclear orphan receptor LXR-beta; nuclear receptor NER; steroid hormone-nuclear receptor NER; ubiquitously-expressed nuclear receptor

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: NR1H2 Target Family: Liver X Receptor Target Protein Species: Human Host Cell Type: RAW264.7; CHO-K1; HEK293
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