NR1H2
The liver X receptors are a nuclear receptor superfamily subfamily that play a critical role in regulating lipid homeostasis and inflammation as well as macrophage activity. In contrast to LXRB, which is found everywhere, inducible LXRA is highly expressed in the liver, adrenal gland, gut, adipose tissue, macrophages, lung, and kidney. Target genes containing LXR response elements are regulated by the production of ligand-activated LXRs, which join forces with retinoid X receptors to form obligatory heterodimers.
Full Name | Nuclear receptor subfamily 1 group H member 2 |
Gene ID | Human: 7376 Mouse: 22260 Rat: 58851 Monkey: 719210 |
UniProt ID | Human: P55055 Mouse: Q60644 Rat: Q62755 Monkey: F7F982 |
Alternative Names | NER; UNR; LXRB; LXR-b; NER-I; RIP15; oxysterols receptor LXR-beta; LX receptor beta; liver X nuclear receptor beta; nuclear orphan receptor LXR-beta; nuclear receptor NER; steroid hormone-nuclear receptor NER; ubiquitously-expressed nuclear receptor |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NR1H2 Target Family: Liver X Receptor Target Protein Species: Human Host Cell Type: RAW264.7; CHO-K1; HEK293