mProX™ Human NR1H2 Stable Cell Line

[CAT#: S01YF-1123-KX100]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Nuclear Receptor

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

NR1H2

Target Family

Liver X Receptor

Target Protein Species

Human

Host Cell Type

RAW264.7; CHO-K1; HEK293

Target Classification

Nuclear Receptor

Target Research Area

Digestive and Renal Research; Reproductive Research

Related Diseases

Complete Androgen Insensitivity Syndrome; Biliary Tract Disease

Gene ID

7376

UniProt ID

P55055

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

A transcription factor belonging to the nuclear receptor family is liver X receptor beta (LXR-β). NR1H2 is the gene that encodes LXR-β. Because it was unknown what their ligands were, the liver X receptors (LXRs) were initially classified as orphan members of the nuclear receptor superfamily. Similar to other receptors in the family, LXRs bind to particular response elements (LXREs), which are defined as direct repeats spaced four nucleotides apart. They also heterodimerize with retinoid X receptor. It is known that two genes, alpha (LXRA) and beta, encode LXR proteins. The customized NR1H2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat David

The performance of the NR1H2 KO cell line was consistent, and the staff was responsive and helpful throughout the process. Jul 08 2021

chat Verified Customer

chat Kathleen

I have tested the NR1H2 cell line as one of the most reliable and versatile options available. Jun 07 2020

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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