NPM1
The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified.
| Full Name | nucleophosmin 1 |
| Gene ID | Human: 4869 Mouse: 18148 Rat: 25498 Monkey: 706883 |
| UniProt ID | Human: P06748 Mouse: Q61937 Rat: P13084 |
| Alternative Names | B23; NPM;nucleophosmin;nucleolar protein NO38;nucleophosmin (nucleolar phosphoprotein B23, numatrin);nucleophosmin/nucleoplasmin family, member 1;testicular tissue protein Li 128 |
Product List
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Magic™ Human NPM1-ALK Assay
[CAT#: S01YF-1222-KX406]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: NPM1-ALK Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human NPM1 Stable Cell Line
[CAT#: S01YF-1023-PY31]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;K562 Assay Types: Biological assays
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