NMBR
This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, a growth factor and mitogen for both healthy and malignant lung tissue as well as the gastrointestinal tract. This receptor might be involved in the control of cell proliferation, neural responses, and smooth muscle contraction. This receptor's antagonists may be used therapeutically to stop the development of tumor cells. NMBR is linked to illnesses including gastrinoma and lung cancer. Class A/1 (Rhodopsin-like receptors) and GPCR downstream signaling are two of its associated pathways. Bombesin receptor activity and G protein-coupled receptor activity are two Gene Ontology (GO) annotations connected to this gene.
| Full Name | Neuromedin B receptor |
| Gene ID | Human: 4829 Mouse: 18101 Rat: 25264 Monkey: 574262 |
| UniProt ID | Human: P28336 Mouse: O54799 Rat: P24053 Monkey: A0A2K6RAL2 |
| Alternative Names | BB1; BB1R; NMB-R; neuromedin-B receptor; bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; epididymis tissue protein Li 185a; neuromedin-B-preferring bombesin receptor; NMBR; Neuromedin B receptor |
Product List
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Magic™ Human FLAG tagged NMBR HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX210]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NMBR Target Family: Bombesin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human NMBR CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX362]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NMBR Target Family: Bombesin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human NMBR CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX25]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NMBR Target Family: Bombesin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ rat FLAG tagged NMBR C6 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX211]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NMBR Target Family: Bombesin Target Protein Species: rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: C6 Assay Types: Calcium flux assay
mProX™ Human NMBR Stable Cell Line
[CAT#: S01YF-0923-PY21]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NMBR Target Family: Bombesin Family Target Protein Species: Human Host Cell Type: Primary myometrial cells;CHO-K1;HEK293
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