NLRP1
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
| Full Name | NLR family pyrin domain containing 1 |
| Gene ID | Human: 22861 Monkey: 721648 |
| UniProt ID | Human: Q9C000 Monkey: H9H2X9 |
| Alternative Names | NAC; JRRP; MSPC; AIADK; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S; NACHT, LRR and PYD domains-containing protein 1; NACHT, LRR and PYD containing protein 1; NACHT, leucine rich repeat and PYD (pyrin domain) containing 1; NACHT, leucine rich repeat and PYD containing 1; caspase recruitment domain protein 7; caspase recruitment domain-containing protein 7; death effector filament-forming Ced-4-like apoptosis protein; nucleotide-binding domain and caspase recruitment domain; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1 |
Product List
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Magic™ Human NLRP1 A549 Cell Line with ASC-GFP Reporter
[CAT#: S01YF-0123-KX355]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NLRP1 Target Family: Others Target Protein Species: Human Host Cell Type: A549 Assay Types: Drug screening and biological assays
mProX™ Human NLRP1 Stable Cell Line
[CAT#: S01YF-1023-PY294]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;WM35;WM115;1205Lu;Hs 294T Assay Types: Biological assays
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