MST1R
This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
| Full Name | macrophage stimulating 1 receptor |
| Gene ID | Human: 4486 Mouse: 19882 Rat: 300999 Monkey: 704437 |
| UniProt ID | Human: Q04912 Mouse: Q62190 Rat: D3ZYM4 |
| Alternative Names | RON; SEA; PTK8; CD136; NPCA3; CDw136; p185-Ron;macrophage-stimulating protein receptor;MSP receptor;PTK8 protein tyrosine kinase 8;S13 avian erythroblastosis oncogene homolog;S13 erythroblastosis oncogene homolog;c-met-related tyrosine kinase |
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mProX™ Human MST1R Stable Cell Line
[CAT#: S01YF-1023-PY89]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;TC71;TC32;Rh30
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