MET
This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers
| Full Name | MET proto-oncogene, receptor tyrosine kinase |
| Gene ID | Human: 4233 Mouse: 17295 Rat: 24553 Monkey: 704562 |
| UniProt ID | Human: P08581 Mouse: P16056 Rat: P97523 |
| Alternative Names | DA11; HGFR; AUTS9; RCCP2; c-Met; DFNB97;hepatocyte growth factor receptor;HGF receptor;HGF/SF receptor;SF receptor;proto-oncogene c-Met;scatter factor receptor;tyrosine-protein kinase Met |
Product List
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Human MET Membrane Protein Bacterial Expression Plasmid
[CAT#: S01YF-1124-KX768]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme Vector: pBE Vector Type: Bacterial Expression Vector
Human MET Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX193]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
Human MET Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1113]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
Human MET Membrane Protein Insect Expression Plasmid
[CAT#: S01YF-1124-KX538]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme Vector: pIE Vector Type: Insect Expression Vector
Human MET Membrane Protein Lentiviral Expression Plasmid
[CAT#: S01YF-1124-KX883]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme Vector: pLV Vector Type: Lentiviral Expression Vector
Human MET Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX78]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme
Human MET Membrane Protein LNP Encapsulation mRNA
[CAT#: S01YF-1124-KX308]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
Human MET Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX423]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme Vector: pME Vector Type: Mammalian Transient Expression Vector
Human TFG & MET Membrane Protein LNP Encapsulation mRNA
[CAT#: S01YF-1124-KX332]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
Human TFG & MET Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX447]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme Vector: pME Vector Type: Mammalian Transient Expression Vector
Human TFG & MET Membrane Protein Retroviral Expression Plasmid
[CAT#: S01YF-1124-KX1022]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme Vector: pRV Vector Type: Retroviral Expression Vector
Human TFG & MET Membrane Protein Yeast Expression Plasmid
[CAT#: S01YF-1124-KX677]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme Vector: pYE Vector Type: Yeast Expression Vector
Human TPR & MET Membrane Protein Bacterial Expression Plasmid
[CAT#: S01YF-1124-KX804]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme Vector: pBE Vector Type: Bacterial Expression Vector
Human TPR & MET Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX229]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
Human TPR & MET Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1149]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
Human TPR & MET Membrane Protein Insect Expression Plasmid
[CAT#: S01YF-1124-KX574]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme Vector: pIE Vector Type: Insect Expression Vector
Human TPR & MET Membrane Protein Lentiviral Expression Plasmid
[CAT#: S01YF-1124-KX919]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme Vector: pLV Vector Type: Lentiviral Expression Vector
Human TPR & MET Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX114]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme
Human TPR & MET Membrane Protein LNP Encapsulation mRNA
[CAT#: S01YF-1124-KX344]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
Human TPR & MET Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX459]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme Vector: pME Vector Type: Mammalian Transient Expression Vector
Human TPR & MET Membrane Protein Retroviral Expression Plasmid
[CAT#: S01YF-1124-KX1034]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme Vector: pRV Vector Type: Retroviral Expression Vector
Human TPR & MET Membrane Protein Yeast Expression Plasmid
[CAT#: S01YF-1124-KX689]
- Product Category:
- Membrane Protein Tools
- Target Protein: TPR; MET Target Family: Kinases/Enzyme Vector: pYE Vector Type: Yeast Expression Vector
Human MET Membrane Protein Retroviral Expression Plasmid
[CAT#: S01YF-1124-KX998]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme Vector: pRV Vector Type: Retroviral Expression Vector
Human MET Membrane Protein Yeast Expression Plasmid
[CAT#: S01YF-1124-KX653]
- Product Category:
- Membrane Protein Tools
- Target Protein: MET Target Family: Kinases/Enzyme Vector: pYE Vector Type: Yeast Expression Vector
Human TFG & MET Membrane Protein Bacterial Expression Plasmid
[CAT#: S01YF-1124-KX792]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme Vector: pBE Vector Type: Bacterial Expression Vector
Human TFG & MET Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX217]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
Human TFG & MET Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1137]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
Human TFG & MET Membrane Protein Insect Expression Plasmid
[CAT#: S01YF-1124-KX562]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme Vector: pIE Vector Type: Insect Expression Vector
Human TFG & MET Membrane Protein Lentiviral Expression Plasmid
[CAT#: S01YF-1124-KX907]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme Vector: pLV Vector Type: Lentiviral Expression Vector
Human TFG & MET Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX102]
- Product Category:
- Membrane Protein Tools
- Target Protein: TFG; MET Target Family: Kinases/Enzyme
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