MERTK
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Full Name | MER proto-oncogene, tyrosine kinase |
Gene ID | Human: 10461 Mouse: 17289 Rat: 65037 Monkey: 698330 |
UniProt ID | Human: Q12866 Mouse: Q60805 Rat: P57097 |
Alternative Names | MER; RP38; c-Eyk; c-mer; Tyro12;tyrosine-protein kinase Mer;MER receptor tyrosine kinase;STK kinase;c-mer proto-oncogene tyrosine kinase;proto-oncogene c-Mer;receptor tyrosine kinase MerTK |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MERTK Target Family: Others Target Protein Species: Human Host Cell Type: B16F10 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MERTK Target Family: Others Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;OCI-AML-5;TMD7