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MC2R

One of the five melanocortin receptors associated with G-proteins is encoded by MC2R. Melanocortins are peptides generated from pro-opiomelanocortin, including melanocyte-stimulating hormone and adrenocorticotropic hormone (POMC). Adrenocorticotropic hormone specifically activates the MC2R, but the other four melanocortin receptors are capable of recognizing a wide range of melanocortin ligands. Familial glucocorticoid insufficiency can be caused by MC2R mutations.

Full Name Melanocortin 2 receptor
Gene ID Human: 4158
Mouse: 17200
Rat: 282839
Monkey: 114673757
UniProt ID Human: Q01718
Mouse: Q64326
Rat: G3V848
Monkey: G7PWB1
Alternative Names ACTHR; adrenocorticotropic hormone receptor; ACTH receptor; MC2 receptor; adrenocorticotropin receptor; corticotropin receptor; melanocortin 2 receptor (adrenocorticotropic hormone); MC2R; Melanocortin 2 receptor

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: MC2R Target Family: Melanocortin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: MC2R Target Family: Melanocortin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: MC2R Target Family: Melanocortin Family Target Protein Species: Mouse Host Cell Type: 3T3-L1;CHO-K1;HEK293
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