MC2R
One of the five melanocortin receptors associated with G-proteins is encoded by MC2R. Melanocortins are peptides generated from pro-opiomelanocortin, including melanocyte-stimulating hormone and adrenocorticotropic hormone (POMC). Adrenocorticotropic hormone specifically activates the MC2R, but the other four melanocortin receptors are capable of recognizing a wide range of melanocortin ligands. Familial glucocorticoid insufficiency can be caused by MC2R mutations.
| Full Name | Melanocortin 2 receptor |
| Gene ID | Human: 4158 Mouse: 17200 Rat: 282839 Monkey: 114673757 |
| UniProt ID | Human: Q01718 Mouse: Q64326 Rat: G3V848 Monkey: G7PWB1 |
| Alternative Names | ACTHR; adrenocorticotropic hormone receptor; ACTH receptor; MC2 receptor; adrenocorticotropin receptor; corticotropin receptor; melanocortin 2 receptor (adrenocorticotropic hormone); MC2R; Melanocortin 2 receptor |
Product List
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Magic™ Human MC2R CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX73]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MC2R Target Family: Melanocortin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
mProX™ Human MC2R Stable Cell Line
[CAT#: S01YF-0923-PY117]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MC2R Target Family: Melanocortin Family Target Protein Species: Mouse Host Cell Type: 3T3-L1;CHO-K1;HEK293
Magic™ Human MC2R CHO-K1 Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX82]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MC2R Target Family: Melanocortin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
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