MAPKAPK5
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported
| Full Name | MAPK activated protein kinase 5 |
| Gene ID | Human: 8550 Mouse: 17165 Rat: 498183 Monkey: 713521 |
| UniProt ID | Human: Q8IW41 Mouse: O54992 Rat: F1LN87 |
| Alternative Names | MK5; MK-5; NCFD; PRAK; MAPKAP-K5;MAP kinase-activated protein kinase 5;MAPKAP kinase 5;MAPKAPK-5;mitogen-activated protein kinase-activated protein kinase 5;p38-regulated/activated protein kinase |
Product List
Loading...
mProX™ Human MAPKAPK5 Stable Cell Line
[CAT#: S01YF-1123-KX298]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MAPKAPK5 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HepG2; Huh7; CHO-K1; HEK293
Can't find the products you're looking for? Optimize our parameters for better results.
Filter By Tag
Note: All of our products are for Research Use Only (RUO). NOT intended for diagnostic, therapeutic or clinical use. We DO NOT offer patients any direct products or services. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
