mProX™ Human MAPKAPK5 Stable Cell Line

[CAT#: S01YF-1123-KX298]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1208	Magic™ Human MAPKAPK5 in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

MAPKAPK5

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

HepG2; Huh7; CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Cardiovascular Research

Related Diseases

Neurocardiofaciodigital Syndrome and Dientamoebiasis. Among its related pathways are Gene expression (Transcription) and Regulation of TP53 Activity

Gene ID

8550

UniProt ID

Q8IW41

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The human MAPKAPK5 gene encodes the enzyme MAP kinase-activated protein kinase 5. This gene codes for a protein that belongs to the family of serine/threonine kinases. By being phosphorylated by MAP kinases, this kinase is activated in response to proinflammatory cytokines and cellular stress. This kinase phosphorylates heat shock protein HSP27 at physiologically significant locations in vitro. This gene has been found to contain two alternatively spliced transcript variants that encode different isoforms. It has been suggested that decreased levels of MAPKAPK5 are related to Alzheimer's disease. The customized MAPKAPK5 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Thomas

The MAPKAPK5 cell line exhibited excellent binding affinity and sensitivity comparable to more expensive alternatives. Jul 11 2020

chat Verified Customer

chat Joseph

The human MAPKAPK5 overexpression cell line is a fantastic solution for researchers. May 19 2021

chat Verified Customer

FAQ

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