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MAP4K5

This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Full Name mitogen-activated protein kinase kinase kinase kinase 5
Gene ID Human: 11183 Mouse: MAP4K5 Rat: 503027 Monkey: 706204
UniProt ID Human: Q9Y4K4 Mouse: Q8BPM2 Rat: D3ZHL6
Alternative Names KHS; GCKR; KHS1; MAPKKKK5;mitogen-activated protein kinase kinase kinase kinase 5;MAPK/ERK kinase kinase kinase 5;MEK kinase kinase 5;MEKKK 5;germinal center kinase-related;kinase homologous to SPS1/STE20

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: MAP4K5 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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