mProX™ Human MAP4K5 Stable Cell Line
[CAT#: S01YF-1123-KX278]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
MAP4K5
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Metabolic Research; Cardiovascular Research
Related Diseases
Among its related pathways are TGF-Beta Pathway and Angiopoietin-like protein 8 regulatory pathway
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The MAP4K5 gene in humans codes for the enzyme mitogen-activated protein kinase kinase kinase 5. The protein kinase belonging to the serine/threonine family that is encoded by this gene bears a striking resemblance to yeast SPS1/STE20 kinase. Near the start of the MAP kinase signal cascades, which are crucial for the yeast pheromone response, is where yeast SPS1/STE20 functions. In mammalian cells, it was demonstrated that this kinase activated Jun kinase, suggesting a function in the stress response. For this gene, two alternatively spliced transcript variants that encode the same protein have been identified. The customized MAP4K5 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Elizabeth
We obtained good data in downstream analysis using this MAP4K5 KO cell line.
Jul 08 2022
Verified Customer
Kevin
A good MAP4K5 cell line. The company obtains a wide range of membrane protein products.
Jan 08 2023
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
