MAP3K11
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42
| Full Name | mitogen-activated protein kinase kinase kinase 11 |
| Gene ID | Human: 4296 Mouse: 26403 Rat: 309168 Monkey: 716038 |
| UniProt ID | Human: Q16584 Mouse: Q80XI6 Rat: Q66HA1 |
| Alternative Names | MLK3; PTK1; SPRK; MLK-3; MEKK11;mitogen-activated protein kinase kinase kinase 11;SH3 domain-containing proline-rich kinase;mixed lineage kinase 3;protein-tyrosine kinase PTK1;src-homology 3 domain-containing proline-rich kinase |
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mProX™ Human MAP3K11 Stable Cell Line
[CAT#: S01YF-1023-PY7]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;SAS
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