LRRK2
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Full Name | leucine rich repeat kinase 2 |
Gene ID | Human: 120892 Mouse: 66725 Rat: 300160 Monkey: 697930 |
UniProt ID | Human: Q5S007 Mouse: Q5S006 Rat: B4F7C3 |
Alternative Names | PARK8; RIPK7; ROCO2; AURA17; DARDARIN;leucine-rich repeat serine/threonine-protein kinase 2;augmented in rheumatoid arthritis 17 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LRRK2 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293