LPAR3
This gene encodes a protein that belongs to the EDG family as well as the G protein-coupled receptor family. This protein promotes lysophosphatidic acid-evoked calcium mobilization and serves as a cellular receptor for lysophosphatidic acid. This receptor primarily binds with G(q/11) alpha proteins. Trachea adenoid cystic carcinoma and tracheal cancer are conditions linked to LPAR3. Actin nucleation by the ARP-WASP complex and GPCR downstream signaling are two of its related pathways.
Full Name | Lysophosphatidic acid receptor 3 |
Gene ID | Human: 23566 Mouse: 65086 Rat: 66025 Monkey: 710828 |
UniProt ID | Human: Q9UBY5 Mouse: Q9EQ31 Rat: Q8K5E0 Monkey: G7NTK3 |
Alternative Names | EDG7; GPCR; LPA3; Edg-7; LP-A3; HOFNH30; RP4-678I3; LPA receptor 3; LPA receptor EDG7; LPA-3; calcium-mobilizing lysophosphatidic acid receptor LP-A3; endothelial cell differentiation gene 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; lysophosphatidic acid receptor Edg-7; LPAR3; Lysophosphatidic acid receptor 3 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LPAR3 Target Family: Lysophospholipid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LPAR3 Target Family: Lysophospholipid Receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LPAR3 Target Family: Lysophospholipid Receptor Target Protein Species: Human Host Cell Type: HEK293T Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LPAR3 Target Family: Lysophospholipid Family Target Protein Species: Rat Host Cell Type: WB-F344;CHO-K1;HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LPAR3 Target Family: Lysophospholipid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: RH7777 Assay Types: Calcium flux assay