LILRB2
This gene belongs to the family of leukocyte immunoglobulin-like receptors (LIR). The encoded protein belongs to the subfamily B class of LIR receptors, which have two to four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is found on immune cells, where it interacts with MHC class I molecules on antigen-presenting cells to provide a signal that prevents the initiation of an immune response. To assist focus the immune response and reduce autoreactivity, it is believed to control cytotoxicity and inflammatory reactions.
Full Name | Leukocyte immunoglobulin like receptor B2 |
Gene ID | Human: 10288 Rat: 65146 |
UniProt ID | Human: Q8N423 Rat: A0A8I5ZNE1 |
Alternative Names | LILRB2; ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10; leukocyte immunoglobulin-like receptor subfamily B member 2; CD85 antigen-like family member D; Ig-like transcript 4; leucocyte Ig-like receptor B2; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2; monocyte/macrophage immunoglobulin-like receptor 10; myeloid inhibitory receptor 10; Leukocyte immunoglobulin like receptor B2 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LILRB2 Target Family: Oncology Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LILRB2 Target Family: Oncology Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: 3A9 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LILRB2 Target Family: Oncology Target Protein Species: Human Host Cell Type: CHO-S Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LILRB2 Target Family: Oncology Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LILRB2 Target Family: Oncology Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MC-38 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LILRB2 Target Family: Oncology Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: THP-1 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Oncology Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HEC-1-A