LATS2
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
| Full Name | large tumor suppressor kinase 2 |
| Gene ID | Human: 26524 Mouse: 50523 Rat: 305922 Monkey: 699957 |
| UniProt ID | Human: Q9NRM7 Mouse: Q7TSJ6 Rat: A0A0G2K4A8 |
| Alternative Names | KPM;serine/threonine-protein kinase LATS2;LATS (large tumor suppressor, Drosophila) homolog 2;LATS, large tumor suppressor, homolog 2;kinase phosphorylated during mitosis protein;large tumor suppressor homolog 2;serine/threonine kinase KPM;serine/threonine-protein kinase kpm;warts-like kinase |
Product List
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mProX™ Human LATS2 Stable Cell Line
[CAT#: S01YF-1123-KX281]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LATS2 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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