LAIR1
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
| Full Name | Leukocyte associated immunoglobulin like receptor 1 |
| Gene ID | Human: 3903 Mouse: 52855 Rat: 574531 Monkey: 105496991 |
| UniProt ID | Human: Q6GTX8 Mouse: Q8BG84 Rat: P0C1X9 Monkey: A0A2K5D1A6 |
| Alternative Names | LAIR1; CD305; LAIR-1; leukocyte-associated immunoglobulin-like receptor 1; immunoglobulin heavy chain variable region; leukocyte-associated Ig-like receptor 1; Leukocyte associated immunoglobulin like receptor 1 |
Product List
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Magic™ Human LAIR1 HEK293T Cell Line
[CAT#: S01YF-0123-KX323]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LAIR1 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
mProX™ Human LAIR1 Stable Cell Line
[CAT#: S01YF-1023-PY276]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Caki-2
Magic™ Human LAIR1 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX207]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: LAIR1 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
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