KISS1R
This gene encodes a protein that functions as a G protein-coupled receptor that binds to the peptide metastin, which is produced by the metastasis suppressor gene KISS1. The fact that this gene appears to be involved in the onset of puberty supports the hypothesis that it is involved in the control of endocrine function based on the tissue distribution of the expressed gene. The Gq/G11 protein-coupled kisspeptin receptor transmits signals by activating phospholipase C. The neuroendocrine regulation of the gonadotrophin axis is significantly influenced by the kisspeptin receptor.
Full Name | KISS1 receptor |
Gene ID | Human: 84634 Mouse: 114229 Rat: 78976 Monkey: 574305 |
UniProt ID | Human: Q969F8 Mouse: Q91V45 Rat: Q924U1 Monkey: F6YBI8 |
Alternative Names | HH8; CPPB1; GPR54; AXOR12; KISS-1R; HOT7T175; kiSS-1 receptor; G protein-coupled receptor 54; G-protein coupled receptor OT7T175; hypogonadotropin-1; kisspeptins receptor; metastin receptor; KISS1R; KISS1 receptor |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KISS1R Target Family: KiSS1-Derived Peptide Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO dhfr- Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KISS1R Target Family: Kisspeptin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KISS1R Target Family: Kisspeptin receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KISS1R Target Family: Kisspeptin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KISS1R Target Family: Kisspeptin receptor Target Protein Species: Human Host Cell Type: MDA-MB-435S Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KISS1R Target Family: KiSS1-Derived Peptide Target Protein Species: Rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO dhfr- Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KISS1R Target Family: KiSS1-derived Peptide Family Target Protein Species: Human Host Cell Type: HT115;CHO-K1;HEK293