KIR2DL1
Transmembrane glycoproteins known as killer cell immunoglobulin-like receptors (KIRs) are expressed by natural killer cells and specific T cell subsets. The length of the cytoplasmic domain (L or S) and the number of extracellular immunoglobulin domains (2 or 3D) are used to categorize KIR proteins. Immune tyrosine-based inhibitory motif (ITIM)-enabled KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding, whereas KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead partner with the TYRO protein tyrosine kinase binding protein to transduce activating signals.
| Full Name | Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 |
| Gene ID | Human: 3802 |
| UniProt ID | Human: P43626 |
| Alternative Names | KIR2DL1; NKAT; NKAT1; p58.1; CD158A; KIR221; NKAT-1; KIR-K64; KIR2DL3; killer cell immunoglobulin-like receptor 2DL1; CD158 antigen-like family member A; KIR2DL protein; KIR2DL1/3DL2; MHC class I NK cell receptor; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1; killer inhibitory receptor 2-2-1; natural killer-associated transcript 1; p58 NK cell inhibitory receptor NKR-K6; p58 NK receptor CL-42/47.11; p58 killer cell inhibitory receptor KIR-K64; p58 natural killer cell receptor clones CL-42/47.11; p58.1 MHC class-I-specific NK receptor; Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 |
Product List
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Magic™ Human KIR2DL1 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX155]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KIR2DL1 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
mProX™ Human KIR2DL1 Stable Cell Line
[CAT#: S01YF-1023-PY182]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;YTS
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