KCNQ3
This gene encodes a protein that controls the excitability of neurons. By joining forces with the by-products of the related KCNQ2 or KCNQ5 genes, which both produce integral membrane proteins, the encoded protein creates an M-channel. M1 muscarinic acetylcholine receptors suppress M-channel currents, while retigabine, a novel anti-convulsant medication, activates them. Epilepsy, benign neonatal type 2, or benign familial neonatal convulsions type 2 are both caused by defects in this gene.
Full Name | Potassium voltage-gated channel subfamily Q member 3 |
Gene ID | Human: 3786 Mouse: 110862 Rat: 29682 Monkey: 700785 |
UniProt ID | Human: O43525 Mouse: Q8K3F6 Rat: O88944 Monkey: F7DI95 |
Alternative Names | EBN2; BFNC2; KV7.3; potassium voltage-gated channel subfamily KQT member 3; potassium channel subunit alpha KvLQT3; potassium channel, voltage gated KQT-like subfamily Q, member 3; potassium channel, voltage-gated, subfamily Q, member 3; potassium voltage-gated channel, KQT-like subfamily, member 3; voltage-gated potassium channel subunit Kv7.3; KCNQ3; Potassium voltage-gated channel subfamily Q member 3 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNQ3 Target Family: Kv7 Target Protein Species: Human Host Cell Type: CHO-K1; HEK293