KCNN3
In vertebrate neurons, action potentials are followed by an afterhyperpolarization (AHP) that may last for many seconds and may have significant effects on the neuron's firing pattern. Each AHP component has its own unique kinetics and is controlled by a unique calcium-activated potassium channel. This gene's protein contributes to the slow portion of synaptic AHP and is hypothesized to control neuronal excitability. The protein is activated prior to membrane hyperpolarization. Together with three other calmodulin-binding subunits, the encoded protein forms an integral membrane protein that functions as a voltage-independent calcium-activated channel. The potassium channel gene KCNN family includes this gene.
| Full Name | Potassium calcium-activated channel subfamily N member 3 |
| Gene ID | Human: 3782 Mouse: 140493 Rat: 54263 Monkey: 574397 |
| UniProt ID | Human: Q9UGI6 Mouse: P58391 Rat: P70605 Monkey: F7ETX9 |
| Alternative Names | KCNN3; SK3; ZLS3; hSK3; SKCA3; KCa2.3; small conductance calcium-activated potassium channel protein 3; SKCa 3; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3; small conductance calcium-activated potassium channel 3; Potassium calcium-activated channel subfamily N member 3 |
Product List
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Magic™ mPro Human KCNN3 Cell Line
[CAT#: S01YF-1122-KX91]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNN3 Target Family: Calcium and Sodium Activated Potassium Channel Target Protein Species: Human
mProX™ Human KCNN3 Stable Cell Line
[CAT#: S01YF-1123-KX40]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNN3 Target Family: SKCa Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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