KCNJ11
Most mammalian cells include potassium channels, which are involved in a variety of physiologic reactions. This gene produces an inward-rectifier type potassium channel that is an integral membrane protein. The encoded protein, which is regulated by G-proteins and is connected to the sulfonylurea receptor SUR, is more likely to allow potassium to flow into cells as opposed to out of them. Familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive condition with uncontrolled insulin production, is caused by mutations in this gene.
| Full Name | Potassium inwardly rectifying channel subfamily J member 11 |
| Gene ID | Human: 3767 Mouse: 16514 Rat: 83535 Monkey: 696722 |
| UniProt ID | Human: Q14654 Mouse: Q61743 Rat: P70673 Monkey: F7HFY6 |
| Alternative Names | BIR; HHF2; PHHI; IKATP; PNDM2; TNDM3; KIR6.2; MODY13; ATP-sensitive inward rectifier potassium channel 11; beta-cell inward rectifier subunit; inward rectifier K(+) channel Kir6.2; inwardly rectifing potassium channel subfamily J member 11; inwardly rectifying potassium channel KIR6.2; inwardly-rectifying potassium channel subfamily J member 11; potassium channel inwardly rectifing subfamily J member 11; potassium channel, inwardly rectifying subfamily J member 11; potassium voltage-gated channel subfamily J member 11; KCNJ11; Potassium inwardly rectifying channel subfamily J member 11 |
Product List
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Magic™ mPro Human KCNJ11/ABCC9 Cell Line
[CAT#: S01YF-1122-KX95]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNJ11/ABCC9 Target Family: Inwardly Rectifying Potassium Channel Target Protein Species: Human
mProX™ Human KCNJ11 Stable Cell Line
[CAT#: S01YF-1123-KX45]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNJ11 Target Family: KATP Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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