KCNA1
Phylogenetically related to the Drosophila Shaker channel, this gene encodes a voltage-gated delayed potassium channel. The encoded protein has six putative transmembrane segments, S1-S6, and the pore and conserved selectivity filter motif are located in the loop between S5 and S6. The homotetramer is the functional channel. Beta subunits connected to the channel's N-terminus have the ability to alter the channel's inactivation characteristics and expression levels. The protein with a PDZ domain complexed to the channel's C-terminus controls channel targeting.
| Full Name | Potassium voltage-gated channel subfamily A member 1 |
| Gene ID | Human: 3736 Mouse: 16485 Rat: 24520 Monkey: 711718 |
| UniProt ID | Human: Q09470 Mouse: P16388 Rat: P10499 Monkey: F7DS72 |
| Alternative Names | EA1; MK1; AEMK; HBK1; HUK1; MBK1; RBK1; KV1.1; potassium voltage-gated channel subfamily A member 1; potassium channel, voltage gated shaker related subfamily A, member 1; potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia); voltage-gated K(+) channel HuKI; voltage-gated potassium channel HBK1; voltage-gated potassium channel subunit Kv1.1; KCNA1; Potassium voltage-gated channel subfamily A member 1 |
Product List
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Magic™ Human KCNA1 CHO-K1 Cell Line, Electrophysiology assay
[CAT#: S01YF-0822-KX558]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNA1 Target Family: Potassium, Inward Rectifier Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Electrophysiology assay
Magic™ Human KCNA10 CHO-K1 Cell Line, Electrophysiology assay
[CAT#: S01YF-0822-KX565]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNA10 Target Family: Potassium, Inward Rectifier Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Electrophysiology assay
Magic™ mPro Human KCNA1 Cell Line
[CAT#: S01YF-1122-KX96]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNA1 Target Family: Voltage Gated Potassium Channel Target Protein Species: Human
mProX™ Human KCNA1 Stable Cell Line
[CAT#: S01YF-1123-KX15]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNA1 Target Family: Kv1 Target Protein Species: Human Host Cell Type: P19; CHO-K1; HEK293
mProX™ Human KCNA10 Stable Cell Line
[CAT#: S01YF-1123-KX22]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KCNA10 Target Family: Kv1 Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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