JAK3
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
| Full Name | Janus kinase 3 |
| Gene ID | Human: 3718 Mouse: 16452 Rat: 24514 Monkey: 694184 |
| UniProt ID | Human: P52333 Mouse: Q62137 Rat: Q63272 |
| Alternative Names | JAKL; LJAK; JAK-3; L-JAK; JAK3_HUMAN;tyrosine-protein kinase JAK3;Janus kinase 3 (a protein tyrosine kinase, leukocyte);leukocyte Janus kinase |
Product List
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mProX™ Human JAK3 Stable Cell Line
[CAT#: S01YF-1123-KX273]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: JAK3 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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