mProX™ Human JAK3 Stable Cell Line
[CAT#: S01YF-1123-KX273]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
JAK3
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Immunology Research; Digestive and Renal Research; Reproductive Research
Related Diseases
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, Nk Cell-Negative and Nk-Cell Enteropathy. Among its related pathways are IL-9 Signaling Pathways and Interleukin-2 family signaling
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Instructions for producing a protein essential to the proper growth and operation of the immune system are provided by the JAK3 gene. The JAK3/STAT pathway is a signaling route that connects the cell's nucleus to external chemical cues. The JAK3 protein is a component of this pathway. The JAK3 protein relays signals that control the development and maturation of T lymphocytes and natural killer cells, two subtypes of white blood cells. JAK3 is also necessary for the proper maturation of B cells, which are a different kind of lymphocyte. In addition to assisting in immune system regulation, T cells, B cells, and natural killer cells combat germs, viruses, and fungus. The customized JAK3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Gary
The human JAK3 KO cell line was an indispensable tool in my research. The cell line's stability and reproducibility were outstanding.
May 23 2020
Verified Customer
Nancy
The JAK3 KO cell line is of high quality and performs exceptionally well in my experiments.
Apr 22 2020
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
