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ITGAE

Integrins are integral membrane proteins that are heterodimeric and made up of an alpha chain and a beta chain. This gene produces an alpha integrin with an I-domain that is cleaved post-translationally in the extracellular domain to produce heavy and light chains that are disulfide-linked. This protein creates the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen when combined with the beta 7 integrin. In addition to playing a part in adhesion, this protein is primarily produced in human intestine intraepithelial lymphocytes (IEL), where it may also operate as an accessory molecule for IEL activation.

Full Name Integrin subunit alpha E
Gene ID Human: 3682
Mouse: 16407
Rat: 83577
Monkey: 721483
UniProt ID Human: P38570
Mouse: Q60677
Rat: M0R6T8
Monkey: H9Z8N2
Alternative Names ITGAE; CD103; HUMINAE; integrin alpha-E; HML-1 antigen; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; human mucosal lymphocyte antigen 1, alpha polypeptide; integrin alpha-IEL; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); mucosal lymphocyte 1 antigen; Integrin subunit alpha E

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: ITGAE Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Product Category:
Membrane Protein Stable Cell Lines
Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1
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