ITGAE
Integrins are integral membrane proteins that are heterodimeric and made up of an alpha chain and a beta chain. This gene produces an alpha integrin with an I-domain that is cleaved post-translationally in the extracellular domain to produce heavy and light chains that are disulfide-linked. This protein creates the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen when combined with the beta 7 integrin. In addition to playing a part in adhesion, this protein is primarily produced in human intestine intraepithelial lymphocytes (IEL), where it may also operate as an accessory molecule for IEL activation.
| Full Name | Integrin subunit alpha E |
| Gene ID | Human: 3682 Mouse: 16407 Rat: 83577 Monkey: 721483 |
| UniProt ID | Human: P38570 Mouse: Q60677 Rat: M0R6T8 Monkey: H9Z8N2 |
| Alternative Names | ITGAE; CD103; HUMINAE; integrin alpha-E; HML-1 antigen; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; human mucosal lymphocyte antigen 1, alpha polypeptide; integrin alpha-IEL; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); mucosal lymphocyte 1 antigen; Integrin subunit alpha E |
Product List
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Magic™ Human ITGAE CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX149]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ITGAE Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
mProX™ Human ITGAE Stable Cell Line
[CAT#: S01YF-1023-PY179]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1 Assay Types: Biological assays
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