IRAK4
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
| Full Name | interleukin 1 receptor associated kinase 4 |
| Gene ID | Human: 51135 Mouse: 266632 Rat: 300177 Monkey: 700568 |
| UniProt ID | Human: Q9NWZ3 Mouse: Q8R4K2 Rat: D4A7K4 |
| Alternative Names | IPD1; IMD67; REN64; IRAK-4; NY-REN-64;interleukin-1 receptor-associated kinase 4;renal carcinoma antigen NY-REN-64 |
Product List
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Magic™ Human IRAK4 Assay
[CAT#: S01YF-1122-KX1173]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: IRAK4 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human IRAK4 Stable Cell Line
[CAT#: S01YF-1123-KX268]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: IRAK4 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: Jurkat; CHO-K1; HEK293
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