IDO1
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
| Full Name | Indoleamine 2,3-dioxygenase 1 |
| Gene ID | Human: 3620 Mouse: 15930 Rat: 66029 Monkey: 574370 |
| UniProt ID | Human: P14902 Mouse: P28776 Rat: Q9ERD9 Monkey: F6SGT6 |
| Alternative Names | IDO; INDO; IDO-1; indoleamine 2,3-dioxygenase 1; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine-pyrrole 2,3-dioxygenase |
Product List
Loading...
Magic™ Human IDO1 HEK293T Cell Line
[CAT#: S01YF-0123-KX289]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: IDO1 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
mProX™ Human IDO1 Stable Cell Line
[CAT#: S01YF-1023-PY274]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;SK-OV-3
Can't find the products you're looking for? Optimize our parameters for better results.
Filter By Tag
Note: All of our products are for Research Use Only (RUO). NOT intended for diagnostic, therapeutic or clinical use. We DO NOT offer patients any direct products or services. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
