HTR2A
One of the serotonin receptors, a neurotransmitter with numerous functions, is encoded by this gene. Mutations in this gene are linked to vulnerability to schizophrenia and obsessive-compulsive disorder, as well as to how well individuals with major depressive disorder respond to the antidepressant citalopram. Citalopram dramatically reduces the response of MDD patients with a mutation in intron 2 of this gene, as this antidepressant downregulates the expression of this gene.
Full Name | 5-hydroxytryptamine receptor 2A |
Gene ID | Human: 3356 Mouse: 15558 Rat: 29595 Monkey: 613032 |
UniProt ID | Human: P28223 Mouse: P35363 Rat: P14842 Monkey: P50128 |
Alternative Names | HTR2; 5-HT2A; 5-HT2 receptor; 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled; serotonin 5-HT-2A receptor; HTR2A; 5-hydroxytryptamine receptor 2A |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HTR2A Target Family: Serotonin Target Protein Species: Dog Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: 5-HT2A Target Family: 5-Hydroxytryptamine Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HTR2A Target Family: Serotonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HTR2A Target Family: 5-Hydroxytryptamine Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HTR2A Target Family: 5-Hydroxytryptamine Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HTR2A Target Family: 5-Hydroxytryptamine Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HTR2A Target Family: 5-Hydroxytryptamine Receptors Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HTR2A Target Family: 5-Hydroxytryptamine Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HTR2A Target Family: Serotonin Target Protein Species: Mouse Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HTR2A Target Family: 5-Hydroxytryptamine Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293