HCN4
A potassium channel that is hyperpolarization-activated and cyclic nucleotide-gated is encoded by this gene. The heart pacemaking mechanism depends on the encoded protein, which has delayed activation and inactivation rates. The responses to sour stimuli may also be mediated by this channel. Sick sinus syndrome 2, commonly known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia, has been linked to mutations in this gene.
| Full Name | Hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| Gene ID | Human: 10021 Mouse: 330953 Rat: 59266 Monkey: 705414 |
| UniProt ID | Human: Q9Y3Q4 Mouse: O70507 Rat: Q9JKA7 Monkey: F6VXL6 |
| Alternative Names | SSS2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; hyperpolarization activated cyclic nucleotide-gated cation channel 4; HCN4; Hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
Product List
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Magic™ mPro Human HCN4 Cell Line
[CAT#: S01YF-1122-KX88]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCN4 Target Family: Hyperpolarized Target Protein Species: Human
mProX™ Human HCN4 Stable Cell Line
[CAT#: S01YF-1123-KX87]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCN4 Target Family: Hyperpolarization-activated, Cyclic Nucleotide-gated Channels Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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