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HCK

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Full Name HCK proto-oncogene, Src family tyrosine kinase
Gene ID Human: 3055 Mouse: 15162 Rat: 25734 Monkey: 715723
UniProt ID Human: P08631 Mouse: P08103 Rat: P50545
Alternative Names JTK9; p59Hck; p61Hck;tyrosine-protein kinase HCK;hematopoietic cell kinase;hemopoietic cell kinase;p59-HCK/p60-HCK

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mProX™ Human HCK Stable Cell Line [CAT#: S01YF-1123-KX254]

Product Category:
Membrane Protein Stable Cell Lines
Target Protein: HCK Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: KG1a; CHO-K1; HEK293
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