HCK
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
| Full Name | HCK proto-oncogene, Src family tyrosine kinase |
| Gene ID | Human: 3055 Mouse: 15162 Rat: 25734 Monkey: 715723 |
| UniProt ID | Human: P08631 Mouse: P08103 Rat: P50545 |
| Alternative Names | JTK9; p59Hck; p61Hck;tyrosine-protein kinase HCK;hematopoietic cell kinase;hemopoietic cell kinase;p59-HCK/p60-HCK |
Product List
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Magic™ Human HCK Assay
[CAT#: S01YF-1122-KX1159]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: HCK Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human HCK Stable Cell Line
[CAT#: S01YF-1123-KX254]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCK Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: KG1a; CHO-K1; HEK293
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