mProX™ Human HCK Stable Cell Line

[CAT#: S01YF-1123-KX254]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1159	Magic™ Human HCK in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

HCK

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

KG1a; CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Cancer Research

Related Diseases

Renal Pelvis Adenocarcinoma and Leukemia, Chronic Myeloid. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and ADORA2B mediated anti-inflammatory cytokines production

Gene ID

3055

UniProt ID

P08631

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Kinase tyrosine-protein The HCK gene in humans codes for the enzyme HCK. The protein-tyrosine kinase that this gene encodes is a member of the Src family of tyrosine kinases and is mostly expressed in hemopoietic cell types. The protein that has been encoded might assist in coupling the Fc receptor to the respiratory burst's activation. In drug-tolerant cancer cells, HCK and the Src family kinases have also been linked to promoting cell survival. Furthermore, it might have an impact on neutrophil migration and degranulation. When a non-AUG (CUG) codon is used as an alternative translation initiation point, two distinct isoforms with distinct subcellular locations are produced. The customized HCK stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Rebecca

The ordering process was smooth, and we received the HCK cell line in perfect condition. Sep 11 2023

chat Verified Customer

chat David

The HCK cell line surpassed my expectations in terms of sensitivity and ease of use. It's now an essential tool in our lab, and we plan to continue using it for future projects. May 23 2021

chat Verified Customer

FAQ

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