HAVCR2
This gene produces a protein that is a member of the TIM family and the immunoglobulin superfamily. Based on the manner in which they secrete cytokines, CD4-positive T helper cells can be classified as either type 1 (Th1) or type 2 (Th2). Th2 cells are involved in the management of external helminthic infections and the promotion of atopic and allergic disorders, whereas Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions. This protein, which is a cell surface Th1-specific molecule, controls macrophage activation, blocks Th1-mediated auto- and alloimmune responses, and fosters immunological tolerance.
Full Name | Hepatitis A virus cellular receptor 2 |
Gene ID | Human: 84868 Mouse: 171285 Rat: 363578 Monkey: 714891 |
UniProt ID | Human: Q8TDQ0 Mouse: Q8VIM0 Rat: P0C0K5 Monkey: F7GB92 |
Alternative Names | HAVCR2; TIM3; CD366; KIM-3; SPTCL; TIMD3; Tim-3; TIMD-3; HAVcr-2; T cell immunoglobulin mucin 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; kidney injury molecule-3; Hepatitis A virus cellular receptor 2 |
Product List
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint Vector: pBE Vector Type: Bacterial Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint Vector: pIE Vector Type: Insect Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint Vector: pLV Vector Type: Lentiviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint Vector: pME Vector Type: Mammalian Transient Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint Vector: pRV Vector Type: Retroviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: HAVCR2 Target Family: Immune Checkpoint Vector: pYE Vector Type: Yeast Expression Vector
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Human primary myometrial cells