HAVCR2
This gene produces a protein that is a member of the TIM family and the immunoglobulin superfamily. Based on the manner in which they secrete cytokines, CD4-positive T helper cells can be classified as either type 1 (Th1) or type 2 (Th2). Th2 cells are involved in the management of external helminthic infections and the promotion of atopic and allergic disorders, whereas Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions. This protein, which is a cell surface Th1-specific molecule, controls macrophage activation, blocks Th1-mediated auto- and alloimmune responses, and fosters immunological tolerance.
| Full Name | Hepatitis A virus cellular receptor 2 |
| Gene ID | Human: 84868 Mouse: 171285 Rat: 363578 Monkey: 714891 |
| UniProt ID | Human: Q8TDQ0 Mouse: Q8VIM0 Rat: P0C0K5 Monkey: F7GB92 |
| Alternative Names | HAVCR2; TIM3; CD366; KIM-3; SPTCL; TIMD3; Tim-3; TIMD-3; HAVcr-2; T cell immunoglobulin mucin 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; kidney injury molecule-3; Hepatitis A virus cellular receptor 2 |
Product List
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Magic™ Human HAVCR2 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX172]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HAVCR2 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Magic™ Human HAVCR2 HEK293T Cell Line
[CAT#: S01YF-0123-KX337]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HAVCR2 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
mProX™ Human HAVCR2 Stable Cell Line
[CAT#: S01YF-1023-PY187]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Human primary myometrial cells
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