Human HAVCR2 Membrane Protein Bacterial Expression Plasmid
[CAT#: S01YF-1124-KX748]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human HAVCR2 for Protein Expression.
Target Protein
HAVCR2
Target Protein Species
Human
Target Classification
Immune Checkpoint
Target Research Area
Cancer Research; Immunology Research
Related Diseases
T-Cell Lymphoma; Subcutaneous Panniculitis-Like; Hepatitis A
Target Family
Immune Checkpoint
Vector
pBE
Vector Type
Bacterial Expression Vector
Note
Resistance
KanR
Growth Temperature
37°C
Relevant Promoters
Lac, T7
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
Protein Expression
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Hepatitis A virus cellular receptor 2
Introduction
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Alternative Names
HAVCR2; TIM3; CD366; KIM-3; SPTCL; TIMD3; Tim-3; TIMD-3; HAVcr-2; T cell immunoglobulin mucin 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; kidney injury molecule-3; Hepatitis A virus cellular receptor 2
Gene ID
UniProt ID
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