GRIN1/GRIN2C
Seven genetically encoded, differently expressed subunits, including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D), and NR3 make up the heterotetramers known as NMDA receptors (GRIN3A or GRIN3B). The early expression of this gene throughout development suggests a function in cellular migration and differentiation, synaptic plasticity, brain development, and circuit construction. Neurodevelopmental disorders such autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia are linked to naturally occurring mutations within this gene.
Full Name | Glutamate ionotropic receptor NMDA type subunit 1 |
Gene ID | Human: 2905 Mouse: 14813 Rat: 24411 Monkey: 699216 |
UniProt ID | Human: Q14957 Mouse: Q01098 Rat: Q00961 Monkey: F6TWJ2 |
Alternative Names | NR1; MRD8; GluN1; NMDA1; NDHMSD; NDHMSR; NMD-R1; NMDAR1; glutamate receptor ionotropic, NMDA 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; glutamate [NMDA] receptor subunit zeta-1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; GRIN1; Glutamate ionotropic receptor NMDA type subunit 1 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRIN1/GRIN2C Target Family: Ligand Gated Ion Channel; Glutamate Receptor Assay Target Protein Species: Human
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRIN1/GRIN2C Target Family: Glutamate Receptor Target Protein Species: Human Host Cell Type: Meg-01; CHO-K1; HEK293