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GRIN1/GRIN2C

Seven genetically encoded, differently expressed subunits, including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D), and NR3 make up the heterotetramers known as NMDA receptors (GRIN3A or GRIN3B). The early expression of this gene throughout development suggests a function in cellular migration and differentiation, synaptic plasticity, brain development, and circuit construction. Neurodevelopmental disorders such autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia are linked to naturally occurring mutations within this gene.

Full Name Glutamate ionotropic receptor NMDA type subunit 1
Gene ID Human: 2905
Mouse: 14813
Rat: 24411
Monkey: 699216
UniProt ID Human: Q14957
Mouse: Q01098
Rat: Q00961
Monkey: F6TWJ2
Alternative Names NR1; MRD8; GluN1; NMDA1; NDHMSD; NDHMSR; NMD-R1; NMDAR1; glutamate receptor ionotropic, NMDA 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; glutamate [NMDA] receptor subunit zeta-1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; GRIN1; Glutamate ionotropic receptor NMDA type subunit 1

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GRIN1/GRIN2C Target Family: Ligand Gated Ion Channel; Glutamate Receptor Assay Target Protein Species: Human
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GRIN1/GRIN2C Target Family: Glutamate Receptor Target Protein Species: Human Host Cell Type: Meg-01; CHO-K1; HEK293
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