GRIN1/GRIN2B
Seven genetically encoded, differently expressed subunits, including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D), and NR3 make up the heterotetramers known as NMDA receptors (GRIN3A or GRIN3B). The early expression of this gene throughout development suggests a function in cellular migration and differentiation, synaptic plasticity, brain development, and circuit construction. Neurodevelopmental disorders such autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia are linked to naturally occurring mutations within this gene.
| Full Name | Glutamate ionotropic receptor NMDA type subunit 1 |
| Gene ID | Human: 2904 Mouse: 14812 Rat: 24410 Monkey: 698571 |
| UniProt ID | Human: Q13224 Mouse: Q01097 Rat: Q00960 Monkey: F6T8S6 |
| Alternative Names | NR1; GluN1; NMDAR1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; NMDA R1 receptor C1 cassette; glutamate [NMDA] receptor subunit zeta-1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; neurotransmitter receptor |
Product List
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Magic™ mPro Human GRIN1/GRIN2B Cell Line
[CAT#: S01YF-1122-KX119]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRIN1/GRIN2B Target Family: Ligand Gated Ion Channel; Glutamate Receptor Assay Target Protein Species: Human
mProX™ Human GRIN1/GRIN2B Stable Cell Line
[CAT#: S01YF-1123-KX71]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRIN1/GRIN2B Target Family: Glutamate Receptor Target Protein Species: Human Host Cell Type: COS-7; CHO-K1; HEK293
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