GPR150
This gene encodes an orphan G-protein-coupled receptor from the class A rhodopsin-like family. This gene belongs to the rhodopsin-like family's vasopressin-like subfamily, which also comprises the oxytocin and vasopressin receptors. The progression of ovarian cancer is linked to the silencing of this gene brought on by promoter methylation. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. The agonist-induced conformational shift in the receptor that activates the heterotrimeric G protein is a characteristic of all GPCR signaling. The various downstream effector proteins that the activated G protein attaches to and activates go on to produce second messengers that mediate a variety of cellular and physiological functions.
| Full Name | G protein-coupled receptor 150 |
| Gene ID | Human: 285601 Mouse: 238725 Rat: 499486 Monkey: 698491 |
| UniProt ID | Human: Q8NGU9 Mouse: Q8BL07 Rat: D3ZHL8 Monkey: F7DA94 |
| Alternative Names | PGR11; probable G-protein coupled receptor 150; seven transmembrane helix receptor; GPR150; G protein-coupled receptor 150 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Orphan Family Target Protein Species: Human Host Cell Type: HEK293;CHO-K1
