GPR149
A member of the G protein coupled receptor (GPCR) class A family with seven transmembranes is encoded by this gene. Despite being a class A GPCR, the encoded protein lacks the first two charged amino acids of the Asp-Arg-Tyr (DRY) motif, which is crucial for effective G protein-coupled signal transduction and is located in the third transmembrane helix of class A receptors. Mice with an orthologous gene deletion are alive and develop ovarian follicles normally, however they have increased fertility and ovulation.
| Full Name | G protein-coupled receptor 149 |
| Gene ID | Human: 344758 Mouse: 229357 Rat: 192251 Monkey: 106997054 |
| UniProt ID | Human: Q86SP6 Mouse: Q3UVY1 Rat: Q924Y8 Monkey: A0A2K6SC75 |
| Alternative Names | R35; IEDA; PGR10; probable G-protein coupled receptor 149; G protein-coupled receptor PGR10; GPR149; G protein-coupled receptor 149 |
Product List
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Magic™ Human GPR149 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX442]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR149 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
mProX™ Human GPR149 Stable Cell Line
[CAT#: S01YF-1023-PY311]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Orphan Family Target Protein Species: Mouse Host Cell Type: Oligodendrocyte precursor cells;CHO-K1;HEK293 Assay Types: Biological assays
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