GPBAR1
A member of the G protein-coupled receptor (GPCR) superfamily is encoded by this gene. This enzyme serves as a bile acid receptor on the cell surface. Bile acid treatment causes the internalization of the receptor, generation of intracellular cAMP, and activation of a MAP kinase signaling pathway in cells that express this GPCR. The receptor is thought to play a role in how bile acids control energy homeostasis and decrease macrophage activity. Sclerosing cholangitis and intrahepatic cholestasis of pregnancy are two conditions linked to GPBAR1. ADORA2B-mediated anti-inflammatory cytokine production and Class A/1 are two of its associated mechanisms (Rhodopsin-like receptors). G protein-coupled receptor activity and G protein-coupled bile acid receptor activity are two Gene Ontology (GO) annotations connected to this gene.
| Full Name | G protein-coupled bile acid receptor 1 |
| Gene ID | Human: 151306 Mouse: 227289 Rat: 338443 Monkey: 103217859 |
| UniProt ID | Human: Q8TDU6 Mouse: Q80SS6 Rat: Q80T02 Monkey: A0A5F7ZTP7 |
| Alternative Names | BG37; TGR5; M-BAR; GPCR19; GPR131; G-protein coupled bile acid receptor 1; G-protein coupled bile acid receptor BG37; G-protein coupled receptor GPCR19; membrane bile acid receptor; membrane-type receptor for bile acids; GPBAR1; G protein-coupled bile acid receptor 1 |
Product List
Loading...
Magic™ Dog GPBAR1 cAMP Assay
[CAT#: S01YF-1122-KX227]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GPBAR1 Target Family: Bile acid Receptor Target Protein Species: Dog Host Cell Type: CHO-K1 Assay Types: cAMP Assay
Magic™ Human FLAG tagged GPBAR1 CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-1022-KX207]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPBAR1 Target Family: Bile Acid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Human GPBAR1 (NM_170699) CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX503]
- Product Category:
- Membranes
- Target Protein: GPBAR1 Target Family: Bile Acid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human GPBAR1 CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-0822-KX415]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPBAR1 Target Family: Bile acid Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Human GPBAR1 HEK293 Cell Line, Calcium flux assay
[CAT#: S01YF-0822-KX432]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPBAR1 Target Family: Bile acid Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293 Assay Types: Calcium flux assay
Magic™ Human GPBAR1 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX79]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPBAR1 Target Family: Bile Acid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human GPBAR1 U2OS Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX414]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPBAR1 Target Family: Bile acid Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Mouse FLAG tagged GPBAR1 CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-1022-KX209]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPBAR1 Target Family: Bile Acid Target Protein Species: Mouse Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Mouse GPBAR1 (BC116914) CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX505]
- Product Category:
- Membranes
- Target Protein: GPBAR1 Target Family: Bile Acid Target Protein Species: Mouse Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Rat FLAG tagged GPBAR1 CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-1022-KX208]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPBAR1 Target Family: Bile Acid Target Protein Species: Rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Rat GPBAR1 (NM_177936.1) CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX504]
- Product Category:
- Membranes
- Target Protein: GPBAR1 Target Family: Bile Acid Target Protein Species: Rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
mProX™ Human GPBAR1 Stable Cell Line
[CAT#: S01YF-0923-PY20]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPBAR1 Target Family: Bile Acid Family Target Protein Species: Human Host Cell Type: SW1353;CHO-K1;HEK293 Assay Types: Biological assays
Can't find the products you're looking for? Optimize our parameters for better results.
Filter By Tag
Note: All of our products are for Research Use Only (RUO). NOT intended for diagnostic, therapeutic or clinical use. We DO NOT offer patients any direct products or services. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
