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GCGR

This gene encodes a glucagon receptor protein, which is crucial for managing blood sugar levels. Diabetes mellitus that is not insulin-dependent is brought on by defects in this gene (NIDDM). G-protein-coupled glucagon receptor that is essential for controlling blood glucose levels and maintaining glucose homeostasis. promotes glycogen hydrolysis and gluconeogenesis, which controls the pace of hepatic glucose synthesis. has a significant impact on how fasting-related reactions are mediated. Guanine nucleotide-binding proteins (G proteins) signal as a result of a conformational change brought on by ligand binding, which also affects the activity of downstream effectors such adenylate cyclase. encourages adenylate cyclase activity.

Full Name Glucagon receptor
Gene ID Human: 2642
Mouse: 14527
Rat: 24953
Monkey: 714542
UniProt ID Human: P47871
Mouse: Q61606
Rat: P30082
Monkey: A0A1D5QZY8
Alternative Names GGR; GL-R; glucagon receptor; GCGR; Glucagon receptor

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 β-Arrestin2 Assay Types: β-Arrestin Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293/Gα15 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon Target Protein Species: Cynomolgus monkey Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon Target Protein Species: Cynomolgus monkey Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon Family Target Protein Species: Human Host Cell Type: HT29;SW480;CHO-K1;HEK293
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GCGR Target Family: Glucagon Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
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