GCGR
This gene encodes a glucagon receptor protein, which is crucial for managing blood sugar levels. Diabetes mellitus that is not insulin-dependent is brought on by defects in this gene (NIDDM). G-protein-coupled glucagon receptor that is essential for controlling blood glucose levels and maintaining glucose homeostasis. promotes glycogen hydrolysis and gluconeogenesis, which controls the pace of hepatic glucose synthesis. has a significant impact on how fasting-related reactions are mediated. Guanine nucleotide-binding proteins (G proteins) signal as a result of a conformational change brought on by ligand binding, which also affects the activity of downstream effectors such adenylate cyclase. encourages adenylate cyclase activity.
Full Name | Glucagon receptor |
Gene ID | Human: 2642 Mouse: 14527 Rat: 24953 Monkey: 714542 |
UniProt ID | Human: P47871 Mouse: Q61606 Rat: P30082 Monkey: A0A1D5QZY8 |
Alternative Names | GGR; GL-R; glucagon receptor; GCGR; Glucagon receptor |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 β-Arrestin2 Assay Types: β-Arrestin Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon Target Protein Species: Cynomolgus monkey Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon Target Protein Species: Cynomolgus monkey Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon Family Target Protein Species: Human Host Cell Type: HT29;SW480;CHO-K1;HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GCGR Target Family: Glucagon Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay